We do condition ourselves to hear things certain ways, but I doubt it's to a very serious extent. I find myself (and others) noticing minuscule changes in people's voices as they gradually grow older, have headcolds, etc., so I can't have conditioned myself too thoroughly; I imagine my subconscious wouldn't allow me to notice, otherwise. This could be poppycock, of course, as I'm not very highly educated about such things.
I don't know about hearing things any differently based on drug intake and the relevant effects; it shouldn't change the functioning of your ears but I know little about how LSD would affect the way your brain processes the information your ears send it. It is a psychotropic drug, so that part of the brain is very likely affected. That's an intriguing thought... I'll have to do some research.
I don't, however, think drugs would allow you to hear something in any more "true" of a way than usual; it could certainly be different, but being truer I find quite doubtful.