We have enormous power; we could destroy the Earth three times over, we can exterminate species at a whim, change our own genetic structures, even. This power will only continue to grow as we become more technologically advanced. I say, why not harness this power for good?
If we correct the flaws that mar the human race, we could eliminate all injustice/poverty/power-lust/blood-lust in our world. If we could create transhumans that did not experience those things in sufficient number, all our problems would be solved.
Of course, there would be the matter of the remaining humans. Also using genetic knowledge, we could engineer an infertility virus that targeted only unenhanced humans, and we would slowly die out.
Some may reject this theory as being cruel, but that is a human flaw.